Seretide Accuhaler

Uses
Seretide Accuhaler (Fluticasone Propionate/Salmeterol) is indicated for the management of symptoms associated with chronic obstructive pulmonary disease (COPD) and asthma. It exhibits anti-inflammatory properties and also relaxes the bronchial smooth muscle. This can help to prevent the occurrence of wheezing, breathing difficulties and asthma attacks (however, it will not provide relief from an asthma attack already underway). Each of the individual ingredients in this medicine exhibit their therapeutic medicines differently, as both belong to separate classes of medications.

Fluticasone is a trifluorinated corticosteroid which is said to be synthetic. It exhibits potent anti-inflammatory activity and acts on many different cells and mediators which contribute to inflammation. One of the contributing factors to breathing difficulties is inflammation in the airways, and by acting on the lungs and airways, this medicine helps to prevent tightening of the airways, thereby making breathing easier. It may even reduce excessive production of mucus.

Salmeterol is known as a selective LABA (long-acting beta2 adrenoceptor agonist), and it works by causing the bronchial smooth muscle to relax. This is achieved by acting on the beta 2 receptors and stimulating and enzyme called adenyl cyclise, allowing the airways to open and remain opened up for up to 12 hours.

Dosage and Administration
Seretide Accuhaler (Fluticasone Propionate/Salmeterol) is provided with an inhalation device that contains 60 blisters. Refer to the instruction leaflet and the directions given by your doctor in order to ensure that it is used properly. The dosage might differ depending on individual circumstances, such as the condition being treated (asthma may require a different dosage to chronic obstructive pulmonary disease). It is normally used on a daily basis, and your doctor will generally tell you to use the lowest dose which can provide effective control of your symptoms.

Side effects
Administration of Seretide Accuhaler (Fluticasone Propionate/Salmeterol) could lead to side effects in some patients, which may include:

• Headache
• Congested nose
• Slight voice changes
• Soreness in the sinus
• Dryness affecting the throat or mouth

Make sure that your doctor is made aware of any reactions which occur. It will be necessary to consult your doctor or to visit the hospital straight away if you notice blurry eyesight, sore eyes, fever, more serious breathing problems, sores on the mouth or any other serious symptoms that have not been mentioned here.

Precautions
This inhaler is not for relieving acute symptoms, and your doctor may direct you to keep a fast acting bronchodilator with you in case this occurs.

It is possible that serious asthma symptoms may be experienced by patients while using this medicine. See your doctor immediately if this happens.

Seek immediate emergency medical attention if you suffer an allergic reaction. Symptoms to watch for, which may be indicative of a reaction, include skin rashes, hives, swelling of the face or limbs, trouble breathing, and trouble swallowing.

Always use Seretide Accuhaler (Fluticasone Propionate/Salmeterol) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.

This medication may not be safe for all patients. Before you begin using it always disclose the following to your doctor:

• If you are pregnant or breastfeeding.
• If you suffer from any allergies.
• If you suffer from any other health conditions or illnesses.
• If you are using any other medicine (including all non-prescription).
• If you are using any supplements, vitamins, or herbal products of any kind.